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The role of RNA folding free energy in the evolution of the polymerase genes of the influenza A virus
BACKGROUND: The influenza A virus genome is composed of eight single-stranded RNA segments of negative polarity. Although the hemagglutinin and neuraminidase genes are known to play a key role in host adaptation, the polymerase genes (which encode the polymerase segments PB2, PB1, PA) and the nucleo...
Autores principales: | Brower-Sinning, Rachel, Carter, Donald M, Crevar, Corey J, Ghedin, Elodie, Ross, Ted M, Benos, Panayiotis V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688270/ https://www.ncbi.nlm.nih.gov/pubmed/19216739 http://dx.doi.org/10.1186/gb-2009-10-2-r18 |
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