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Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages

YKL-39 is a Glyco_18 domain containing chitinase-like protein which is currently recognized as a biomarker for the activation of chondrocytes and the progress of the osteoarthritis in human. YKL-39 was identified as an abundantly secreted protein in primary culture of human articular chondrocytes. T...

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Detalles Bibliográficos
Autores principales: Gratchev, Alexei, Schmuttermaier, Christina, Mamidi, Srinivas, Gooi, LiMing, Goerdt, Sergij, Kzhyshkowska, Julia
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688341/
https://www.ncbi.nlm.nih.gov/pubmed/19578492