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Effect of Ca(v)β Subunits on Structural Organization of Ca(v)1.2 Calcium Channels

BACKGROUND: Voltage-gated Ca(v)1.2 calcium channels play a crucial role in Ca(2+) signaling. The pore-forming α(1C) subunit is regulated by accessory Ca(v)β subunits, cytoplasmic proteins of various size encoded by four different genes (Ca(v)β(1) - β(4)) and expressed in a tissue-specific manner. ME...

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Detalles Bibliográficos
Autores principales: Kobrinsky, Evgeny, Abrahimi, Parwiz, Duong, Son Q., Thomas, Sam, Harry, Jo Beth, Patel, Chirag, Lao, Qi Zong, Soldatov, Nikolai M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688388/
https://www.ncbi.nlm.nih.gov/pubmed/19492014
http://dx.doi.org/10.1371/journal.pone.0005587