An endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei

Trypanosoma brucei is the causative agent of African Sleeping Sickness in humans and one of the causes of Nagana in cattle. This protozoan parasite evades the host immune system by antigenic variation, a periodic switching of its variant surface glycoprotein (VSG) coat. VSG switching is spontaneous...

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Detalles Bibliográficos
Autores principales: Boothroyd, Catharine E., Dreesen, Oliver, Leonova, Tatyana, Ly, K. Ina, Figueiredo, Luisa M., Cross, George A.M., Papavasiliou, F. Nina
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688456/
https://www.ncbi.nlm.nih.gov/pubmed/19369939
http://dx.doi.org/10.1038/nature07982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688456/
https://www.ncbi.nlm.nih.gov/pubmed/19369939
http://dx.doi.org/10.1038/nature07982

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