Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

Genome-wide association studies are revolutionizing the search for the genes underlying human complex diseases. The main decisions to be made at the design stage of these studies are the choice of the commercial genotyping chip to be used and the numbers of case and control samples to be genotyped....

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Detalles Bibliográficos
Autores principales: Spencer, Chris C. A., Su, Zhan, Donnelly, Peter, Marchini, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688469/
https://www.ncbi.nlm.nih.gov/pubmed/19492015
http://dx.doi.org/10.1371/journal.pgen.1000477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688469/
https://www.ncbi.nlm.nih.gov/pubmed/19492015
http://dx.doi.org/10.1371/journal.pgen.1000477

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