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Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip
Genome-wide association studies are revolutionizing the search for the genes underlying human complex diseases. The main decisions to be made at the design stage of these studies are the choice of the commercial genotyping chip to be used and the numbers of case and control samples to be genotyped....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688469/ https://www.ncbi.nlm.nih.gov/pubmed/19492015 http://dx.doi.org/10.1371/journal.pgen.1000477 |