Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

It is widely accepted that reactive oxygen species (ROS) promote tumorigenesis. However, the exact mechanisms are still unclear. As mice lacking the peroxidase peroxiredoxin1 (Prdx1) produce more cellular ROS and die prematurely of cancer, they offer an ideal model system to study ROS-induced tumori...

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Detalles Bibliográficos
Autores principales: Cao, Juxiang, Schulte, Jennifer, Knight, Alexander, Leslie, Nicholas R, Zagozdzon, Agnieszka, Bronson, Roderick, Manevich, Yefim, Beeson, Craig, Neumann, Carola A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688529/
https://www.ncbi.nlm.nih.gov/pubmed/19369943
http://dx.doi.org/10.1038/emboj.2009.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688529/
https://www.ncbi.nlm.nih.gov/pubmed/19369943
http://dx.doi.org/10.1038/emboj.2009.101

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