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In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography

Background. The use of 2-[(18)F]fluoro-2-deoxy-D-glucose ([(18)F]FDG) may help to establish the antitumor activity of enzastaurin, a novel protein kinase C-beta II (PKC-βII) inhibitor, in mouse xenografts. Methods. The hematologic cell line RAJI and the solid tumor cell line U87MG were each implante...

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Detalles Bibliográficos
Autores principales: Pollok, Karen E., Lahn, Michael, Enas, Nathan, McNulty, Ann, Graff, Jeremy, Cai, Shanbao, Hartwell, Jennifer R., Ernstberger, Aaron, Thornton, Donald, Brail, Les, Hutchins, Gary
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688651/
https://www.ncbi.nlm.nih.gov/pubmed/19503801
http://dx.doi.org/10.1155/2009/596560