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EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42
Subversion of the eukaryotic cell cytoskeleton is a virulence strategy employed by many bacterial pathogens. Due to the pivotal role of Rho GTPases in actin dynamics they are common targets of bacterial effector proteins and toxins. IpgB1, IpgB2 (Shigella), SifA, SifB (Salmonella) and Map and EspM (...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688677/ https://www.ncbi.nlm.nih.gov/pubmed/19016787 http://dx.doi.org/10.1111/j.1462-5822.2008.01248.x |