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High Specificity of Quantitative Methylation-Specific PCR Analysis for MGMT Promoter Hypermethylation Detection in Gliomas

Normal brain tissue from 28 individuals and 50 glioma samples were analyzed by real-time Quantitative Methylation-Specific PCR (QMSP). Data from this analysis were compared with results obtained on the same samples by MSP. QMSP analysis demonstrated a statistically significant difference in both met...

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Detalles Bibliográficos
Autores principales: Parrella, Paola, la Torre, Antonella, Copetti, Massimiliano, Valori, Vanna M., Barbano, Raffaela, Notarangelo, Angelo, Bisceglia, Michele, Gallo, Antonietta Pia, Balsamo, Teresa, Poeta, Maria Luana, Carella, Massimo, Catapano, Domenico, Parisi, Salvatore, Dallapiccola, Bruno, Maiello, Evaristo, D'Angelo, Vincenzo, Fazio, Vito Michele
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688744/
https://www.ncbi.nlm.nih.gov/pubmed/19503806
http://dx.doi.org/10.1155/2009/531692