Evolutionary Pressure on Mitochondrial Cytochrome b Is Consistent with a Role of CytbI7T Affecting Longevity during Caloric Restriction

BACKGROUND: Metabolism of energy nutrients by the mitochondrial electron transport chain (ETC) is implicated in the aging process. Polymorphisms in core ETC proteins may have an effect on longevity. Here we investigate the cytochrome b (cytb) polymorphism at amino acid 7 (cytbI7T) that distinguishes...

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Detalles Bibliográficos
Autores principales: Beckstead, Wesley A., Ebbert, Mark T. W., Rowe, Mark J., McClellan, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688749/
https://www.ncbi.nlm.nih.gov/pubmed/19503808
http://dx.doi.org/10.1371/journal.pone.0005836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688749/
https://www.ncbi.nlm.nih.gov/pubmed/19503808
http://dx.doi.org/10.1371/journal.pone.0005836

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