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A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen

Damage initiates a pleiotropic cellular response aimed at cellular survival when appropriate. To identify genes required for damage survival, we used a cell-based RNAi screen against the Drosophila genome and the alkylating agent methyl methanesulphonate (MMS). Similar studies performed in other mod...

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Detalles Bibliográficos
Autores principales: Ravi, Dashnamoorthy, Wiles, Amy M., Bhavani, Selvaraj, Ruan, Jianhua, Leder, Philip, Bishop, Alexander J. R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688755/
https://www.ncbi.nlm.nih.gov/pubmed/19543366
http://dx.doi.org/10.1371/journal.pgen.1000527