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A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen
Damage initiates a pleiotropic cellular response aimed at cellular survival when appropriate. To identify genes required for damage survival, we used a cell-based RNAi screen against the Drosophila genome and the alkylating agent methyl methanesulphonate (MMS). Similar studies performed in other mod...
Autores principales: | Ravi, Dashnamoorthy, Wiles, Amy M., Bhavani, Selvaraj, Ruan, Jianhua, Leder, Philip, Bishop, Alexander J. R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688755/ https://www.ncbi.nlm.nih.gov/pubmed/19543366 http://dx.doi.org/10.1371/journal.pgen.1000527 |
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