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Nucleocytoplasmic Shuttling Activity of Ataxin-3

Spinocerebellar ataxia type-3, also known as Machado-Joseph Disease (MJD), is one of many inherited neurodegenerative disorders caused by polyglutamine-encoding CAG repeat expansions in otherwise unrelated genes. Disease protein misfolding and aggregation, often within the nucleus of affected neuron...

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Detalles Bibliográficos
Autores principales: Macedo-Ribeiro, Sandra, Cortes, Luísa, Maciel, Patrícia, Carvalho, Ana Luísa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688764/
https://www.ncbi.nlm.nih.gov/pubmed/19503814
http://dx.doi.org/10.1371/journal.pone.0005834