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Avoiding Dangerous Missense: Thermophiles Display Especially Low Mutation Rates
Rates of spontaneous mutation have been estimated under optimal growth conditions for a variety of DNA-based microbes, including viruses, bacteria, and eukaryotes. When expressed as genomic mutation rates, most of the values were in the vicinity of 0.003–0.004 with a range of less than two-fold. Bec...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688765/ https://www.ncbi.nlm.nih.gov/pubmed/19543367 http://dx.doi.org/10.1371/journal.pgen.1000520 |