Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotype

INTRODUCTION: The tumour-suppressive effects of transforming growth factor-beta (TGF-β) are well documented; however, the mechanistic basis of these effects is not fully understood. Previously, we showed that a non-canonical member of the Wingless-related protein family, Wnt5a, is required for TGF-β...

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Detalles Bibliográficos
Autores principales: Roarty, Kevin, Baxley, Sarah E, Crowley, Michael R, Frost, Andra R, Serra, Rosa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688948/
https://www.ncbi.nlm.nih.gov/pubmed/19344510
http://dx.doi.org/10.1186/bcr2244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688948/
https://www.ncbi.nlm.nih.gov/pubmed/19344510
http://dx.doi.org/10.1186/bcr2244

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