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Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms

INTRODUCTION: The stromal microenvironment has a profound influence on tumour cell behaviour. In tumours, the extracellular matrix (ECM) composition differs from normal tissue and allows novel interactions to influence tumour cell function. The ECM protein tenascin-C (TNC) is frequently up-regulated...

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Detalles Bibliográficos
Autores principales: Hancox, Rachael A, Allen, Michael D, Holliday, Deborah L, Edwards, Dylan R, Pennington, Caroline J, Guttery, David S, Shaw, Jacqueline A, Walker, Rosemary A, Pringle, J Howard, Jones, J Louise
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688953/
https://www.ncbi.nlm.nih.gov/pubmed/19405959
http://dx.doi.org/10.1186/bcr2251