siRNA-based targeting of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cells

BACKGROUND: High expression of P-glycoprotein is one of the well-known mechanisms of chemoresistance in chondrosarcomas. However, the role of antiapoptotic proteins, a common mechanism responsible for chemoresistance in other tumors, has not been well studied in chondrosarcomas. We examined the impo...

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Detalles Bibliográficos
Autores principales: Kim, Dae Won, Kim, Kyung-Ok, Shin, Mike J, Ha, Jung Hee, Seo, Sung Wook, Yang, Jay, Lee, Francis Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689171/
https://www.ncbi.nlm.nih.gov/pubmed/19445670
http://dx.doi.org/10.1186/1476-4598-8-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689171/
https://www.ncbi.nlm.nih.gov/pubmed/19445670
http://dx.doi.org/10.1186/1476-4598-8-28

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