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Incomplete posttranslational prohormone modifications in hyperactive neuroendocrine cells

BACKGROUND: In black-background-adapted Xenopus laevis, the intermediate pituitary melanotrope cells are hyperactive, producing large amounts of their major secretory cargo proopiomelanocortin (POMC, representing ~80% of all newly synthesised proteins), whereas in white-adapted frogs these cells are...

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Detalles Bibliográficos
Autores principales: Strating, Jeroen RPM, Martens, Gerard JM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689178/
https://www.ncbi.nlm.nih.gov/pubmed/19422674
http://dx.doi.org/10.1186/1471-2121-10-35