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Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection

BACKGROUND: Current small animal models for studying HIV-1 infection are very limited, and this continues to be a major obstacle for studying HIV-1 infection and pathogenesis, as well as for the urgent development and evaluation of effective anti-HIV-1 therapies and vaccines. Previously, it was show...

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Detalles Bibliográficos
Autores principales: Blanco, Jorge CG, Pletneva, Lioubov M, Wieczorek, Lindsay, Khetawat, Dimple, Stantchev, Tzanko S, Broder, Christopher C, Polonis, Victoria R, Prince, Gregory A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689193/
https://www.ncbi.nlm.nih.gov/pubmed/19442298
http://dx.doi.org/10.1186/1743-422X-6-57