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Additive effect of LRP8/APOER2 R952Q variant to APOE ε2/ε3/ε4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study

BACKGROUND: The R952Q variant in the low density lipoprotein receptor-related protein 8 (LRP8)/apolipoprotein E receptor 2 (ApoER2) gene has been recently associated with familial and premature myocardial infarction (MI) by means of genome-wide linkage scan/association studies. We were interested in...

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Detalles Bibliográficos
Autores principales: Martinelli, Nicola, Olivieri, Oliviero, Shen, Gong-Qing, Trabetti, Elisabetta, Pizzolo, Francesca, Busti, Fabiana, Friso, Simonetta, Bassi, Antonella, Li, Lin, Hu, Ying, Pignatti, Pier Franco, Corrocher, Roberto, Wang, Qing Kenneth, Girelli, Domenico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689206/
https://www.ncbi.nlm.nih.gov/pubmed/19439088
http://dx.doi.org/10.1186/1471-2350-10-41