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Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor

BACKGROUND: Controlling enzyme activity by ligand binding to a regulatory domain of choice may have many applications e.g. as biosensors and as tools in regulating cellular functions. However, until now only a small number of ligand-binding domains have been successfully linked to enzyme activity. G...

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Detalles Bibliográficos
Autores principales: Thor, Doreen, Le Duc, Diana, Strotmann, Rainer, Schöneberg, Torsten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689208/
https://www.ncbi.nlm.nih.gov/pubmed/19450256
http://dx.doi.org/10.1186/1472-6750-9-46