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Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis

BACKGROUND: Nitric oxide (NO) can be both pro- and anti-apoptotic in various cell types, including macrophages. This apparent paradox may result from the actions of NO-related species generated in the microenvironment of the cell, for example the formation of peroxynitrite (ONOO(-)). In this study w...

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Detalles Bibliográficos
Autores principales: Shaw, Catherine A, Webb, David J, Rossi, Adriano G, Megson, Ian L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689212/
https://www.ncbi.nlm.nih.gov/pubmed/19422695
http://dx.doi.org/10.1186/1476-9255-6-14