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Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis

BACKGROUND: The 19 kDa lipoprotein of Mycobacterium tuberculosis (MTB) is an important target of the innate immune response. To investigate the effect of post-translation modification of this protein on innate recognition in the context of the whole bacillus, we derived a recombinant M. tuberculosis...

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Detalles Bibliográficos
Autores principales: Wilkinson, Katalin A, Newton, Sandra M, Stewart, Graham R, Martineau, Adrian R, Patel, Janisha, Sullivan, Susan M, Herrmann, Jean-Louis, Neyrolles, Olivier, Young, Douglas B, Wilkinson, Robert J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689228/
https://www.ncbi.nlm.nih.gov/pubmed/19442300
http://dx.doi.org/10.1186/1471-2180-9-93