The diamidine DB75 targets the nucleus of Plasmodium falciparum

BACKGROUND: DB289, [2,5-bis(4-amidinophenyl)furan bis-O-methylamidoxime], is a broad spectrum anti-parasitic compound which has been shown to be effective against malaria in recent clinical trials. DB75, [2,5-bis(4-amidinophenyl)furan], is the active metabolite of this drug. The objective of this st...

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Detalles Bibliográficos
Autores principales: Purfield, Anne E, Tidwell, Richard R, Meshnick, Steven R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689252/
https://www.ncbi.nlm.nih.gov/pubmed/19442305
http://dx.doi.org/10.1186/1475-2875-8-104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689252/
https://www.ncbi.nlm.nih.gov/pubmed/19442305
http://dx.doi.org/10.1186/1475-2875-8-104

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