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Haplotype specific-sequencing reveals MBL2 association with asymptomatic Plasmodium falciparum infection

BACKGROUND: Mannose binding lectin (MBL) has an important role in the activation of the complement system and opsonization of pathogenic microorganisms. Frequent polymorphisms found in the MBL2 gene affect the concentration and functionality of the protein and are associated with enhanced susceptibi...

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Detalles Bibliográficos
Autores principales: Boldt, Angelica BW, Messias-Reason, Iara J, Lell, Bertrand, Issifou, Saadou, Pedroso, Maria Lucia Alves, Kremsner, Peter G, Kun, Jürgen FJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689254/
https://www.ncbi.nlm.nih.gov/pubmed/19432958
http://dx.doi.org/10.1186/1475-2875-8-97