Cargando…

Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5

BACKGROUND: Stat5 is a latent transcription factor that regulates essential growth and survival functions in normal cells. Constitutive activity of Stat5 and the involvement of its C-terminally truncated variant have been implicated in blood cell malignancies and mammary or breast cancer. To disting...

Descripción completa

Detalles Bibliográficos
Autores principales: Eilon, Tali, Barash, Itamar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689279/
https://www.ncbi.nlm.nih.gov/pubmed/19450255
http://dx.doi.org/10.1186/1471-2164-10-231