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Motor Mechanism for Protein Threading through Hsp104
The protein-remodeling machine Hsp104 dissolves amorphous aggregates as well as ordered amyloid assemblies such as yeast prions. Force generation originates from a tandem AAA+ (ATPases associated with various cellular activities) cassette, but the mechanism and allostery of this action remain to be...
Autores principales: | , , , , , , |
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格式: | Texto |
語言: | English |
出版: |
Cell Press
2009
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主題: | |
在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689388/ https://www.ncbi.nlm.nih.gov/pubmed/19362537 http://dx.doi.org/10.1016/j.molcel.2009.02.026 |