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Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes

BACKGROUND: Dendritic cell (DC) defects may contribute to chronicity in hepatitis C virus (HCV) infection and determine response to PEG–interferon and ribavirin therapy via poor T cell stimulation. Studies to date have produced inconsistent results regarding DC maturation and function: no large stud...

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Detalles Bibliográficos
Autores principales: Mengshol, J A, Golden-Mason, L, Castelblanco, N, Im, K A, Dillon, S M, Wilson, C C, Rosen, H R
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689392/
https://www.ncbi.nlm.nih.gov/pubmed/19193669
http://dx.doi.org/10.1136/gut.2008.168948