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Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins
A lattice-model study of double-mutant cycles published in BMC Structural Biology underscores how interactions in non-native conformations can lead to thermodynamic coupling between distant residues in globular proteins, adding to recent advances in delineating the often crucial roles played by diso...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689430/ https://www.ncbi.nlm.nih.gov/pubmed/19344476 http://dx.doi.org/10.1186/jbiol126 |