Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease

A 100 kb region on 9p21.3 harbors two major disease susceptibility loci: one for type 2 diabetes (T2D) and one for coronary heart disease (CHD). The single nucleotide polymorphisms (SNPs) associated with these two diseases in Europeans reside on two adjacent haplotype blocks with independent effects...

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Detalles Bibliográficos
Autores principales: Silander, Kaisa, Tang, Hua, Myles, Sean, Jakkula, Eveliina, Timpson, Nicholas J, Cavalli-Sforza, Luigi, Peltonen, Leena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689443/
https://www.ncbi.nlm.nih.gov/pubmed/19463184
http://dx.doi.org/10.1186/gm51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689443/
https://www.ncbi.nlm.nih.gov/pubmed/19463184
http://dx.doi.org/10.1186/gm51

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