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Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease
A 100 kb region on 9p21.3 harbors two major disease susceptibility loci: one for type 2 diabetes (T2D) and one for coronary heart disease (CHD). The single nucleotide polymorphisms (SNPs) associated with these two diseases in Europeans reside on two adjacent haplotype blocks with independent effects...
Autores principales: | Silander, Kaisa, Tang, Hua, Myles, Sean, Jakkula, Eveliina, Timpson, Nicholas J, Cavalli-Sforza, Luigi, Peltonen, Leena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689443/ https://www.ncbi.nlm.nih.gov/pubmed/19463184 http://dx.doi.org/10.1186/gm51 |
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