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Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis

OBJECTIVE: To evaluate the efficacy and toxicity of methotrexate (MTX) monotherapy compared with MTX combination with non-biological disease-modifying antirheumatic drugs (DMARDs) in adults with rheumatoid arthritis. METHOD: A systematic review of randomised trials comparing MTX alone and in combina...

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Detalles Bibliográficos
Autores principales: Katchamart, W, Trudeau, J, Phumethum, V, Bombardier, C
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689526/
https://www.ncbi.nlm.nih.gov/pubmed/19054823
http://dx.doi.org/10.1136/ard.2008.099861