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Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis
OBJECTIVE: To evaluate the efficacy and toxicity of methotrexate (MTX) monotherapy compared with MTX combination with non-biological disease-modifying antirheumatic drugs (DMARDs) in adults with rheumatoid arthritis. METHOD: A systematic review of randomised trials comparing MTX alone and in combina...
Autores principales: | Katchamart, W, Trudeau, J, Phumethum, V, Bombardier, C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689526/ https://www.ncbi.nlm.nih.gov/pubmed/19054823 http://dx.doi.org/10.1136/ard.2008.099861 |
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