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Gene Conversion Transfers the GAF-A Domain of Phosphodiesterase TbrPDEB1 to One Allele of TbrPDEB2 of Trypanosoma brucei

BACKGROUND: Chromosome 9 of Trypanosoma brucei contains two closely spaced, very similar open reading frames for cyclic nucleotide specific phosphodiesterases TbrPDEB1 and TbrPDEB2. They are separated by 2379 bp, and both code for phosphodiesterases with two GAF domains in their N-terminal moieties...

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Detalles Bibliográficos
Autores principales: Kunz, Stefan, Luginbuehl, Edith, Seebeck, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689650/
https://www.ncbi.nlm.nih.gov/pubmed/19513125
http://dx.doi.org/10.1371/journal.pntd.0000455