Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region

Translation termination at premature termination codons (PTCs) triggers degradation of the aberrant mRNA, but the mechanism by which a termination event is defined as premature is still unclear. Here we show that the physical distance between the termination codon and the poly(A)-binding protein PAB...

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Detalles Bibliográficos
Autores principales: Eberle, Andrea B, Stalder, Lukas, Mathys, Hansruedi, Orozco, Rodolfo Zamudio, Mühlemann, Oliver
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689704/
https://www.ncbi.nlm.nih.gov/pubmed/18447580
http://dx.doi.org/10.1371/journal.pbio.0060092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689704/
https://www.ncbi.nlm.nih.gov/pubmed/18447580
http://dx.doi.org/10.1371/journal.pbio.0060092

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