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Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region
Translation termination at premature termination codons (PTCs) triggers degradation of the aberrant mRNA, but the mechanism by which a termination event is defined as premature is still unclear. Here we show that the physical distance between the termination codon and the poly(A)-binding protein PAB...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689704/ https://www.ncbi.nlm.nih.gov/pubmed/18447580 http://dx.doi.org/10.1371/journal.pbio.0060092 |