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PER3 Polymorphism Predicts Cumulative Sleep Homeostatic but Not Neurobehavioral Changes to Chronic Partial Sleep Deprivation

BACKGROUND: The variable number tandem repeat (VNTR) polymorphism 5-repeat allele of the circadian gene PERIOD3 (PER3(5/5)) has been associated with cognitive decline at a specific circadian phase in response to a night of total sleep deprivation (TSD), relative to the 4-repeat allele (PER3(4/4)). P...

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Detalles Bibliográficos
Autores principales: Goel, Namni, Banks, Siobhan, Mignot, Emmanuel, Dinges, David F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689932/
https://www.ncbi.nlm.nih.gov/pubmed/19516903
http://dx.doi.org/10.1371/journal.pone.0005874