Intraluminal Blockade of Cell-Surface CD74 and Glucose Regulated Protein 78 Prevents Substance P-Induced Bladder Inflammatory Changes in the Rat

BACKGROUND: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine constitutively expressed by urothelial cells. During inflammatory stimuli, MIF is released into the lumen complexed to other proteins and these complexes can bind to urothelial cell-surface receptors to activate...

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Detalles Bibliográficos
Autores principales: Vera, Pedro L., Wang, Xihai, Bucala, Richard J., Meyer-Siegler, Katherine L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690654/
https://www.ncbi.nlm.nih.gov/pubmed/19503733
http://dx.doi.org/10.1371/journal.pone.0005835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690654/
https://www.ncbi.nlm.nih.gov/pubmed/19503733
http://dx.doi.org/10.1371/journal.pone.0005835

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