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Arylbenzazepines Are Potent Modulators for the Delayed Rectifier K(+) Channel: A Potential Mechanism for Their Neuroprotective Effects

(±) SKF83959, like many other arylbenzazepines, elicits powerful neuroprotection in vitro and in vivo. The neuroprotective action of the compound was found to partially depend on its D(1)-like dopamine receptor agonistic activity. The precise mechanism for the (±) SKF83959-mediated neuroprotection r...

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Detalles Bibliográficos
Autores principales: Chen, Xue-Qin, Zhang, Jing, Neumeyer, John L., Jin, Guo-Zhang, Hu, Guo-Yuan, Zhang, Ao, Zhen, Xuechu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690691/
https://www.ncbi.nlm.nih.gov/pubmed/19503734
http://dx.doi.org/10.1371/journal.pone.0005811