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Arylbenzazepines Are Potent Modulators for the Delayed Rectifier K(+) Channel: A Potential Mechanism for Their Neuroprotective Effects
(±) SKF83959, like many other arylbenzazepines, elicits powerful neuroprotection in vitro and in vivo. The neuroprotective action of the compound was found to partially depend on its D(1)-like dopamine receptor agonistic activity. The precise mechanism for the (±) SKF83959-mediated neuroprotection r...
Autores principales: | Chen, Xue-Qin, Zhang, Jing, Neumeyer, John L., Jin, Guo-Zhang, Hu, Guo-Yuan, Zhang, Ao, Zhen, Xuechu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690691/ https://www.ncbi.nlm.nih.gov/pubmed/19503734 http://dx.doi.org/10.1371/journal.pone.0005811 |
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