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The QKI-6 and QKI-7 RNA Binding Proteins Block Proliferation and Promote Schwann Cell Myelination

BACKGROUND: The quaking viable (qk(v)) mice have uncompacted myelin in their central and peripheral nervous system (CNS, PNS). The qk gene encodes 3 major alternatively spliced isoforms that contain unique sequence at their C-terminus dictating their cellular localization. QKI-5 is a nuclear isoform...

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Detalles Bibliográficos
Autores principales: Larocque, Daniel, Fragoso, Gabriela, Huang, Jinghan, Mushynski, Walter E., Loignon, Martin, Richard, Stéphane, Almazan, Guillermina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690695/
https://www.ncbi.nlm.nih.gov/pubmed/19517016
http://dx.doi.org/10.1371/journal.pone.0005867