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Directed Mammalian Gene Regulatory Networks Using Expression and Comparative Genomic Hybridization Microarray Data from Radiation Hybrids

Meiotic mapping of quantitative trait loci regulating expression (eQTLs) has allowed the construction of gene networks. However, the limited mapping resolution of these studies has meant that genotype data are largely ignored, leading to undirected networks that fail to capture regulatory hierarchie...

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Detalles Bibliográficos
Autores principales: Ahn, Sangtae, Wang, Richard T., Park, Christopher C., Lin, Andy, Leahy, Richard M., Lange, Kenneth, Smith, Desmond J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690838/
https://www.ncbi.nlm.nih.gov/pubmed/19521529
http://dx.doi.org/10.1371/journal.pcbi.1000407