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Directed Mammalian Gene Regulatory Networks Using Expression and Comparative Genomic Hybridization Microarray Data from Radiation Hybrids
Meiotic mapping of quantitative trait loci regulating expression (eQTLs) has allowed the construction of gene networks. However, the limited mapping resolution of these studies has meant that genotype data are largely ignored, leading to undirected networks that fail to capture regulatory hierarchie...
Autores principales: | Ahn, Sangtae, Wang, Richard T., Park, Christopher C., Lin, Andy, Leahy, Richard M., Lange, Kenneth, Smith, Desmond J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690838/ https://www.ncbi.nlm.nih.gov/pubmed/19521529 http://dx.doi.org/10.1371/journal.pcbi.1000407 |
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