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Functional Equivalency Inferred from “Authoritative Sources” in Networks of Homologous Proteins

A one-on-one mapping of protein functionality across different species is a critical component of comparative analysis. This paper presents a heuristic algorithm for discovering the Most Likely Functional Counterparts (MoLFunCs) of a protein, based on simple concepts from network theory. A key featu...

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Detalles Bibliográficos
Autores principales: Natarajan, Shreedhar, Jakobsson, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690840/
https://www.ncbi.nlm.nih.gov/pubmed/19521530
http://dx.doi.org/10.1371/journal.pone.0005898