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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling

PURPOSE: To determine the mechanisms of Signal Transducer and Activator of Transcription 1 (Stat1)-associated radioresistance developed by nu61 tumour selected in vivo by fractionated irradiation of the parental radiosensitive tumour SCC61. MATERIALS AND METHODS: Radioresistence of nu61 and SCC61 in...

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Detalles Bibliográficos
Autores principales: Efimova, Elena V., Liang, Hua, Pitroda, Sean P., Labay, Edwardine, Darga, Thomas E., Levina, Vera, Lokshin, Anna, Roizman, Bernard, Weichselbaum, Ralph R., Khodarev, Nikolai N.
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690884/
https://www.ncbi.nlm.nih.gov/pubmed/19437244
http://dx.doi.org/10.1080/09553000902838566