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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately 1.3 gigabytes. Bowtie extends prev...

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Detalles Bibliográficos
Autores principales: Langmead, Ben, Trapnell, Cole, Pop, Mihai, Salzberg, Steven L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690996/
https://www.ncbi.nlm.nih.gov/pubmed/19261174
http://dx.doi.org/10.1186/gb-2009-10-3-r25