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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately 1.3 gigabytes. Bowtie extends prev...
Autores principales: | Langmead, Ben, Trapnell, Cole, Pop, Mihai, Salzberg, Steven L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690996/ https://www.ncbi.nlm.nih.gov/pubmed/19261174 http://dx.doi.org/10.1186/gb-2009-10-3-r25 |
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