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Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

BACKGROUND: The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently found to be expressed also in the central nervous system. In addition, G-CSF...

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Detalles Bibliográficos
Autores principales: Frank, Tobias, Schlachetzki, Johannes CM, Göricke, Bettina, Meuer, Katrin, Rohde, Gundula, Dietz, Gunnar PH, Bähr, Mathias, Schneider, Armin, Weishaupt, Jochen H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691410/
https://www.ncbi.nlm.nih.gov/pubmed/19442279
http://dx.doi.org/10.1186/1471-2202-10-49