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Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy
BACKGROUND: The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently found to be expressed also in the central nervous system. In addition, G-CSF...
Autores principales: | Frank, Tobias, Schlachetzki, Johannes CM, Göricke, Bettina, Meuer, Katrin, Rohde, Gundula, Dietz, Gunnar PH, Bähr, Mathias, Schneider, Armin, Weishaupt, Jochen H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691410/ https://www.ncbi.nlm.nih.gov/pubmed/19442279 http://dx.doi.org/10.1186/1471-2202-10-49 |
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